|
Symbol Name ID |
Fxn
frataxin MGI:1096879 |
| Darker colors indicate more annotations |
| Human Phenotypes | Areflexia of lower limbs |
Abnormality of visual evoked potentials |
Ataxia |
Gait ataxia |
Limb ataxia |
Babinski sign |
Decreased sensory nerve conduction velocity |
Decreased amplitude of sensory action potentials |
Dysarthria |
Sensory neuropathy |
Impaired proprioception |
Impaired vibratory sensation |
| Disease(s) Associated with FXN | ||||||||||||
| Friedreich ataxia 1 |
| Mouse Phenotypes | abnormal axon morphology |
decreased myelin sheath thickness |
retina photoreceptor degeneration |
dorsal root ganglion degeneration |
neurodegeneration |
spongiform encephalopathy |
abnormal nerve conduction |
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| Availability | Mouse Genotype | |||||||
| Gt(ROSA)26Sortm1(H1/tetO-RNAi:Fxn)Dhg/Gt(ROSA)26Sor+ | ||||||||
| Fxntm2Mkn/Fxntm2.1Mkn Tg(Eno2-cre)39Jme/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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